Oxidative stress, genotoxicity and histopathology biomarker responses in mullet (Mugil cephalus) and sea bass (Dicentrarchus labrax) liver from Bizerte Lagoon (Tunisia)     

Ben Ameur W  de Lapuente J  El Megdiche Y  Barhoumi B  Trabelsi S  Camps L  Serret J  Ramos-López D  Gonzalez-Linares J  Driss MR  Borràs M 《Marine pollution bulletin》2012,64(2):241-251

The aim of the study was to evaluate the impact of environmental contaminants on oxidative stress, genotoxic and histopathologic biomarkers in liver of mullet (Mugil cephalus) and sea bass (Dicentrarchus labrax) collected from a polluted coastal lagoon (Bizerte Lagoon) in comparison to a reference site (the Mediterranean Sea). Antioxidant enzyme activities were lower in fish from the polluted site compared with fish from the reference site, suggesting deficiency of the antioxidant system to compensate for oxidative stress. DNA damage was higher in both fish species from the contaminated site indicating genotoxic effects. The liver histopathological analysis revealed alterations in fish from Bizerte Lagoon. Hepatocytes from both fish species featured extensive lipid-type vacuolation and membrane disruption. Results suggest that the selected biomarkers in both fish species are useful for the assessment of pollution impacts in coastal environments influenced by multiple pollution sources.  相似文献   

Critical point families at the 3:1 resonance     

Miquel Grau 《Celestial Mechanics and Dynamical Astronomy》1995,61(4):389-401

An enlarged averaged Hamiltonian is introduced to compute some families of periodic orbits of the planar elliptic 3-body problem, in the Sun-Jupiter-Asteroid system, near the 3:1 resonance. Five resonant families are found and their stability is studied, The families of symmetric periodic orbits of the elliptic problem appear near the corresponding fixed points which have been computed in this model and the coincidence is good for moderate values of the eccentricity of the asteroid for two of these families; the other three families do not fulfil the Sundman condition and they cannot be considered as families of periodic orbits of the real model.  相似文献   

Improving Bayesian analysis for LISA Pathfinder using an efficient Markov Chain Monte Carlo method     

Luigi Ferraioli  Edward K. Porter  Michele Armano  Heather Audley  Giuseppe Congedo  Ingo Diepholz  Ferran Gibert  Martin Hewitson  Mauro Hueller  Nikolaos Karnesis  Natalia Korsakova  Miquel Nofrarias  Eric Plagnol  Stefano Vitale 《Experimental Astronomy》2014,37(1):109-125

We present a parameter estimation procedure based on a Bayesian framework by applying a Markov Chain Monte Carlo algorithm to the calibration of the dynamical parameters of the LISA Pathfinder satellite. The method is based on the Metropolis-Hastings algorithm and a two-stage annealing treatment in order to ensure an effective exploration of the parameter space at the beginning of the chain. We compare two versions of the algorithm with an application to a LISA Pathfinder data analysis problem. The two algorithms share the same heating strategy but with one moving in coordinate directions using proposals from a multivariate Gaussian distribution, while the other uses the natural logarithm of some parameters and proposes jumps in the eigen-space of the Fisher Information matrix. The algorithm proposing jumps in the eigen-space of the Fisher Information matrix demonstrates a higher acceptance rate and a slightly better convergence towards the equilibrium parameter distributions in the application to LISA Pathfinder data. For this experiment, we return parameter values that are all within ～1σ of the injected values. When we analyse the accuracy of our parameter estimation in terms of the effect they have on the force-per-unit of mass noise, we find that the induced errors are three orders of magnitude less than the expected experimental uncertainty in the power spectral density.  相似文献   

Intra-clinothem variability in sedimentary texture and process regime recorded down slope profiles     

Grace I. E. Cosgrove  Miquel Poyatos-Moré  David R. Lee  David M. Hodgson  William D. McCaffrey  Nigel P. Mountney 《Sedimentology》2020,67(1):431-456

Shelf-margin clinothem successions can archive process interactions at the shelf to slope transition, and their architecture provides constraints on the interplay of factors that control basin-margin evolution. However, detailed textural analysis and facies distributions from shelf to slope transitions remain poorly documented. This study uses quantitative grain-size and sorting data from coeval shelf and slope deposits of a single clinothem that crops out along a 5 km long, dip-parallel transect of the Eocene Sobrarbe Deltaic Complex (Ainsa Basin, south-central Pyrenees, Spain). Systematic sampling of sandstone beds tied to measured sections has captured vertical and basinward changes in sedimentary texture and facies distributions at an intra-clinothem scale. Two types of hyperpycnal flow-related slope deposits, both rich in mica and terrestrial organic matter, are differentiated according to grain size, sorting and bed geometry: (i) sustained hyperpycnal flow deposits, which are physically linked to coarse channelized sediments in the shelf setting and which deposit sand down the complete slope profile; (ii) episodic hyperpycnal flow deposits, which are disconnected from, and incise into, shelf sands and which are associated with sediment bypass of the proximal slope and coarse-grained sand deposition on the medial and distal slope. Both types of hyperpycnites are interbedded with relatively homogenous, organic-free and mica-free, well-sorted, very fine-grained sandstones, which are interpreted to be remobilized from wave-dominated shelf environments; these wave-dominated deposits are found only on the proximal and medial slope. Coarse-grained sediment bypass into the deeper-water slope settings is therefore dominated by episodic hyperpycnal flows, whilst sustained hyperpycnal flows and turbidity currents remobilizing wave-dominated shelf deposits are responsible for the full range of grain sizes in the proximal and medial slope, thus facilitating clinoform progradation. This novel dataset highlights previously undocumented intra-clinothem variability related to updip changes in the shelf process-regime, which is therefore a key factor controlling downdip architecture and resulting sedimentary texture.  相似文献   

风生紊流导致微囊藻群体破碎和形态变化   总被引：1，自引：0，他引：1  

朱伟  陈怀民  肖曼  Lurling Miquel  李明 《湖泊科学》2021,33(2):349-365

微囊藻群体大小和形态决定其垂向迁移能力,从而影响着水华的形成.为了探讨湖泊中风生紊流对微囊藻群体大小和形态的影响,本研究于2012年8月26日至9月7日在太湖梅梁湾的围隔内进行了12 d的昼夜不间断的高频采样（采样间隔每2小时一次）.研究期间,水面微囊藻密度呈现4次周期性消涨,藻密度变化范围为4×10⁴~2671×10⁴ cells/mL.而整个水柱中的藻密度变化范围仅为3×10⁴~18×10⁴ cells/mL.皮尔逊相关性分析表明微囊藻的原位生长速率与表面藻密度呈负相关而与风速呈正相关.强风速使微囊藻在水柱中均匀分散,增强了透光性,促进了微囊藻的生长.微囊藻群体粒径随着风速的增大逐渐减小,反之亦然.其中值粒径（D₅₀）变化范围为66.2~768.0 μm.在此期间微囊藻群体形态主要以鱼害微囊藻、不规则的惠氏微囊藻、球状的惠氏微囊藻和铜绿微囊藻群体形态为主,其占比也呈现出波动状态.皮尔逊相关分析结果显示微囊藻群体大小与风速呈负相关,说明湖泊中风生紊流会影响微囊藻群体大小.当紊流强度为2.33×10^-5 m²/s³时,微囊藻群体会发生破碎现象,该紊流强度相当于5 m/s的风在30 m深的水库或湖泊中所产生的紊流强度.微囊藻群体被风生紊流破碎后最大粒径与该风速下紊流的最小涡旋尺度相近,表明紊流的最小涡旋尺度决定了微囊藻所能形成群体的最终大小.监测期间,整水柱中不同群体形态的微囊藻占比发生了明显变化,在监测初期以鱼害微囊藻群体形态为主,随后不规则的惠氏微囊藻和铜绿微囊藻群体形态的比例不断增加,最后鱼害微囊藻群体形态又占据主导地位.球状的惠氏微囊藻群体形态在整个监测期中的比例随时间的增加而逐渐降低.不同群体形态微囊藻之间比例的大幅变化无法用微囊藻生长演替来解释.而皮尔逊相关分析结果显示鱼害微囊藻与惠氏微囊藻（不规则的和球状的惠氏微囊藻之和）群体形态之间存在负相关,且惠氏微囊藻与铜绿微囊藻群体形态呈负相关.但在今后研究中需进一步关注在微囊藻群体形态的动态变化过程中细胞大小、胶被、产毒特性和基因序列等特征,从而验证不同种微囊藻群体是否存在形态转换这一猜想.总而言之,普通强度的风生紊流能够破碎微囊藻群体,而气候变化导致的内陆湖泊周边风速下降会促使微囊藻形成更大的群体,从而有利于水华的形成.  相似文献